The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2013

Filed:

Dec. 26, 2007
Applicants:

Kazutoshi Watanabe, Kanagawa, JP;

Toshiyuki Kohara, Kanagawa, JP;

Kenji Fukunaga, Kanagawa, JP;

Fumiaki Uehara, Kanagawa, JP;

Inventors:

Kazutoshi Watanabe, Kanagawa, JP;

Toshiyuki Kohara, Kanagawa, JP;

Kenji Fukunaga, Kanagawa, JP;

Fumiaki Uehara, Kanagawa, JP;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound represented by the formula (I), an optically active isomer thereof, or a pharmaceutical acceptable salt thereof: wherein each Rrepresents hydrogen atom or the like; X represents oxygen atom or the like; A represents a C-Ccycloalkyl group, a C-Caryl group or a heterocyclic group; Rrepresents a halogen atom or the like; s represents 0 or an integer of 1 to 5; Q represents a pyridine ring which may be substituted or pyrimidine ring; and Rrepresents hydrogen atom or the like, which is used for preventive and/or therapeutic treatment of a disease caused by abnormal activity of tau protein kinase 1 such as a neurodegenerative diseases (e.g. Alzheimer disease).


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