The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2013
Filed:
Feb. 11, 2010
Haiching MA, Malvern, PA (US);
Sorin Vasile Filip, Wadebridge, GB;
Matthew Alexander Henry, Camelford, GB;
James Alexander Dolan, Truro, GB;
Bartosz Dietrich, Plymouth, GB;
Haiching Ma, Malvern, PA (US);
Sorin Vasile Filip, Wadebridge, GB;
Matthew Alexander Henry, Camelford, GB;
James Alexander Dolan, Truro, GB;
Bartosz Dietrich, Plymouth, GB;
Reaction Biology Corp., Woodbridge, CT (US);
Synerga Limited, London, GB;
Abstract
The present invention relates to methods of modulating (for example, inhibiting) activity of JAK3, comprising contacting the JAK3 with a compound of Formula I: or pharmaceutically acceptable salt thereof, wherein constituent members are provided hereinwith. The present invention further provides novel compounds and compositions as well as their methods of preparation and use of the same as JAK3 inhibitors in the treatment of JAK3-associated diseases including, for example, inflammatory and autoimmune disorders.