The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2013
Filed:
Jun. 14, 2012
Xianhai Huang, Warren, NJ (US);
Jason Brubaker, Cambridge, MA (US);
Scott L. Peterson, Salem, MA (US);
John W. Butcher, Berlin, MA (US);
Joshua T. Close, Franklin, MA (US);
Michelle Martinez, Medford, MA (US);
Rachel Nicola Maccoss, Oxford, GB;
Joon O. Jung, Newton, MA (US);
Phieng Siliphaivanh, Newton, MA (US);
Hongjun Zhang, Newton, MA (US);
Robert G. Aslanian, Rockaway, NJ (US);
Purakkattle Johny Biju, Piscataway, NJ (US);
LI Dong, Roselle Park, NJ (US);
Ying Huang, Berkeley Heights, NJ (US);
Kevin D. Mccormick, Basking Ridge, NJ (US);
Anandan Palani, Bridgewater, NJ (US);
Ning Shao, Watchung, NJ (US);
Wei Zhou, Scotch Plains, NJ (US);
Xianhai Huang, Warren, NJ (US);
Jason Brubaker, Cambridge, MA (US);
Scott L. Peterson, Salem, MA (US);
John W. Butcher, Berlin, MA (US);
Joshua T. Close, Franklin, MA (US);
Michelle Martinez, Medford, MA (US);
Rachel Nicola MacCoss, Oxford, GB;
Joon O. Jung, Newton, MA (US);
Phieng Siliphaivanh, Newton, MA (US);
Hongjun Zhang, Newton, MA (US);
Robert G. Aslanian, Rockaway, NJ (US);
Purakkattle Johny Biju, Piscataway, NJ (US);
Li Dong, Roselle Park, NJ (US);
Ying Huang, Berkeley Heights, NJ (US);
Kevin D. McCormick, Basking Ridge, NJ (US);
Anandan Palani, Bridgewater, NJ (US);
Ning Shao, Watchung, NJ (US);
Wei Zhou, Scotch Plains, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I), and their pharmaceutically acceptable salts and esters, wherein R, R, R, R, R, E, Y, Z, n, u, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTHfunction.