The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2013
Filed:
Mar. 31, 2006
Applicants:
Hideyoshi Harashima, Hokkaido, JP;
Shiroh Futaki, Kyoto, JP;
Kentaro Kogure, Hokkaido, JP;
Inventors:
Assignee:
Japan Science and Technology Agency, Saitama, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 9/127 (2006.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
Abstract
With the object of providing a liposome having cellular and nuclear entry ability, to achieve this object, a liposome is provided having on its surface a peptide comprising multiple consecutive arginine residues, and specifically a liposome is provided wherein the peptide is modified with a hydrophobic group or hydrophobic compound and the hydrophobic group or hydrophobic compound is inserted into a lipid bilayer so that the peptide is exposed on the surface of the bilayer.