The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2013
Filed:
Mar. 07, 2012
Mahesh V. Padval, Needham, MA (US);
Jeff T. Gautschi, Bend, OR (US);
Daniel T. Smithey, Bend, OR (US);
Marshall D. Crew, Bend, OR (US);
Abizer Harianawala, Acton, MA (US);
Mahesh V. Padval, Needham, MA (US);
Jeff T. Gautschi, Bend, OR (US);
Daniel T. Smithey, Bend, OR (US);
Marshall D. Crew, Bend, OR (US);
Abizer Harianawala, Acton, MA (US);
Zalicus Pharmaceuticals Ltd., Vancouver, CA;
Abstract
The present invention relates to formulations and methods for increasing the bioavailability of 1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one, 1-(3,3-diphenylpropanoyl)piperazine, or a salt thereof. In particular, the formulation can include one or more pharmaceutically acceptable matrix polymers to form a solid dispersion, e.g., a spray dried dispersion or a hot melt extrusion.