The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 26, 2013
Filed:
Feb. 14, 2007
Junbo GE, Shandong, CN;
Shenguo Wang, Shandong, CN;
Jianzhong Bei, Shandong, CN;
Haijun Zhang, Shandong, CN;
Xiangfei Wang, Shandong, CN;
Xiaoxin Shang, Shandong, CN;
Haihong Guo, Shandong, CN;
Junbo Ge, Shandong, CN;
Shenguo Wang, Shandong, CN;
Jianzhong Bei, Shandong, CN;
Haijun Zhang, Shandong, CN;
Xiangfei Wang, Shandong, CN;
Xiaoxin Shang, Shandong, CN;
Haihong Guo, Shandong, CN;
Shangdong Intech Medical Technology Co., Ltd, Shandong, CN;
Abstract
A coronary stent is provided with asymmetric drug releasing controlled coating used in interventional therapy of coronary disease, containing a bare stent and a coating consisting of drug and carrier, the coating is coated onto the outer wall surface of the bare stent, and is multi-layered. The drug concentration in the coating increases in sequence from the outer layer to the inner layer. The drugs used in different layers of the coating may be identical or different, and particularly may be one or more selected from taxol, rapamycin, heparin, docetaxel and a combination thereof. The carrier may be a random (lactide-glycolide) copolymer having a molecular weight of 50,000-200,000. The drug-coated stent of the present invention employs highly effective drugs, enabling a thinnest coating and reducing the vascular irritation. The drug release is regulated by altering the coating manner so as to satisfy the clinical requirement for controlled drug release. The employed asymmetric coating promotes regenerative repairing of vascular endothelium. The present invention is a drug-coated coronary stent with reasonable design, with the coating capable of effectively preventing vascular restenosis and reducing occurrence of late thrombosis.