The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2013

Filed:

Nov. 07, 2011
Applicants:

Michelle Bradley, Horsham, GB;

Zarin Brown, Reigate, GB;

Steven John Charlton, Horsham, GB;

Karen Cromie, Merelbeke, BE;

Bruno Dombrecht, Heusden, BE;

Soren Steffensen, Gent, BE;

Gino Van Heeke, Upper Beeding, GB;

Inventors:

Michelle Bradley, Horsham, GB;

Zarin Brown, Reigate, GB;

Steven John Charlton, Horsham, GB;

Karen Cromie, Merelbeke, BE;

Bruno Dombrecht, Heusden, BE;

Soren Steffensen, Gent, BE;

Gino Van Heeke, Upper Beeding, GB;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/46 (2006.01); C12N 15/13 (2006.01); C12N 15/62 (2006.01); C12N 5/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to polypeptides directed against or specifically binding to chemokine receptor CXCR2 and in particular to polypeptides capable of modulating signal transduction from CXCR2. The invention also relates to nucleic acids, vectors and host cells capable of expressing the polypeptides of the invention, pharmaceutical compositions comprising the polypeptides and uses of said polypeptides and compositions for treatment of diseases involving aberrant functioning of CXCR2.


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