The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2013
Filed:
Sep. 10, 2012
Hsyueh-liang Wu, Taipei, TW;
Chun-chih Chen, Taipei, TW;
Chia-chen Liu, Taipei, TW;
Wei-ting Wei, Taipei, TW;
Jo-hsuan Fang, Taipei, TW;
Hsyueh-Liang Wu, Taipei, TW;
Chun-Chih Chen, Taipei, TW;
Chia-Chen Liu, Taipei, TW;
Wei-Ting Wei, Taipei, TW;
Jo-Hsuan Fang, Taipei, TW;
National Taiwan Normal University, Taipei, TW;
Abstract
The present invention proposes a chiral diene ligand, a fabrication method thereof and applications thereof. The chiral diene ligand is a bicyclo[2.2.1] diene ligand having structural specificity and high stability, which favors the bicyclo[2.2.1] diene ligand to take part in asymmetric transformations, particularly an asymmetric addition reaction involving a metal catalyst in a basic environment. Most of the products of the reactions implemented by the chiral diene ligands of the present invention have superior optical activity. The method of the present invention comprises a first oxidation step, a saponification step, a second oxidation step, a deprotonation step, and a cross-coupling step. The chiral diene ligand of the present invention is very suitable to be used in the fabrication or synthesis of various chemicals and medical products.