The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8586768 B1

PDF
Full Text
Expired
Date of Patent:
Nov. 19, 2013

Filed:

Nov. 12, 2010
Applicants:

Anumantha G. Kanthasamy, Ames, IA (US);

George A. Kraus, Ames, IA (US);

Vellareddy Anantharam, Gilbert, IA (US);

Inventors:

Anumantha G. Kanthasamy, Ames, IA (US);

George A. Kraus, Ames, IA (US);

Vellareddy Anantharam, Gilbert, IA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/58 (2006.01); C07D 311/70 (2006.01); A61K 31/352 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of synthesizing rottlerin analogs is described. The synthesis methods described are the first known method of synthesizing rottlerin analogs from commercially-available materials to produce cost effective analogs. Rottlerin analog structures made by the synthesis methods and methods of use for treating a neurological or inflammatory response mediated by protein kinase C (PKC) are further described.


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