The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 19, 2013

Filed:

Dec. 17, 2008
Applicants:

Shuan Dong, Watchung, NJ (US);

Jeonghan Park, Whippany, NJ (US);

Eugene John Vater, Lyndhurst, NJ (US);

Inventors:

Shuan Dong, Watchung, NJ (US);

Jeonghan Park, Whippany, NJ (US);

Eugene John Vater, Lyndhurst, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 231/12 (2006.01); C07C 231/06 (2006.01); C07C 237/14 (2006.01); C07D 209/52 (2006.01);
U.S. Cl.
CPC ...
Abstract

A process for preparing 3-amino-3-cyclobutylmethyl-2-hydroxypropionamide of the Formula I: or a salt thereof involves providing a compound of the Formula VI described herein in a solution comprising predominately dimethylsulfoxide (DMSO) and converting this compound directly to the compound of the Formula VIII described herein without working up or isolating the intermediate compound of the Formula VII described herein.


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