The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2013
Filed:
Jun. 12, 2007
Stephanie Hachtel, Frankfurt, DE;
Heinrich Christian Englert, Hofheim, DE;
Uwe Gerlach, Hattersheim, DE;
Heinz Goegelein, Frankfurt, DE;
Holger Heitsch, Mainz-Kastel, DE;
Karl-heinz Lehr, Frankfurt, DE;
Stefania Pfeiffer-marek, Frankfurt, DE;
Stephanie Hachtel, Frankfurt, DE;
Heinrich Christian Englert, Hofheim, DE;
Uwe Gerlach, Hattersheim, DE;
Heinz Goegelein, Frankfurt, DE;
Holger Heitsch, Mainz-Kastel, DE;
Karl-Heinz Lehr, Frankfurt, DE;
Stefania Pfeiffer-Marek, Frankfurt, DE;
Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;
Abstract
The present invention relates to piperidinesulfonylureas and piperidinesulfonylthioureas of formula I, in which A, X, R(1), R(2) and R(3) have the meanings indicated in the claims. The compounds of formula I are valuable active pharmaceutical ingredients which show in particular an inhibiting effect on ATP-sensitive potassium channels of the cardiac muscle and are suitable, for example, for the treatment of disorders of the cardiovascular system such as coronary heart disease, arrhythmias, cardiac insufficiency, cardiomyopathies or reduced contractility of the heart or for the prevention of sudden cardiac death. The invention further relates to processes for preparing the compounds of formula I, their use and pharmaceutical compositions comprising them.