The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2013
Filed:
Nov. 24, 2009
Axel Becker, Darmstadt, DE;
Clemens Kuehn, Darmstadt, DE;
Christoph Saal, Otzberg, DE;
Oliver Schadt, Rodenbach, DE;
Dieter Dorsch, Ober-Ramstadt, DE;
Eva Kriegbaum, Darmstadt, DE;
Frank Stieber, Heidelberg, DE;
Cristina Donini, Geneva, CH;
Axel Becker, Darmstadt, DE;
Clemens Kuehn, Darmstadt, DE;
Christoph Saal, Otzberg, DE;
Oliver Schadt, Rodenbach, DE;
Dieter Dorsch, Ober-Ramstadt, DE;
Eva Kriegbaum, Darmstadt, DE;
Frank Stieber, Heidelberg, DE;
Cristina Donini, Geneva, CH;
Merck Patent GmbH, Darmstadt, DE;
Abstract
The present invention relates to 6-(1-methyl-1H-pyrazol-4-yl)-2-{3-[5-(2-morpholin-4-yl-ethoxy)-pyrimidin-2-yl]-benzyl}-2H-pyridazin-3-one dihydrogenphosphate, its solvates and crystalline modifications thereof. The present invention further relates to processes of manufacturing these crystalline modifications as well as their use in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by the inhibition, regulation and/or modulation of signal transduction of kinases, in particular by the inhibition of tyrosine kinases, e.g. pathophysiological conditions such as cancer.