The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 19, 2013

Filed:

Jul. 17, 2012
Applicants:

Denis Carniato, Marcoussis, FR;

Caroline Leriche, Paris, FR;

Didier Roche, Saclay, FR;

Christine Charon, Gometz-le-Chatel, FR;

Liliane Doare, Viry-Chatillon, FR;

Inventors:

Denis Carniato, Marcoussis, FR;

Caroline Leriche, Paris, FR;

Didier Roche, Saclay, FR;

Christine Charon, Gometz-le-Chatel, FR;

Liliane Doare, Viry-Chatillon, FR;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 243/08 (2006.01); C07D 487/04 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to diazepane-acetamide derivatives of formula I as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) and the use of such compounds for the treatment and prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions.


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