The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2013
Filed:
Mar. 12, 2010
Kai Fan, Jiulongpo Chongqing, CN;
Chun Zhang, Jiulongpo Chongqing, CN;
Xuefeng MA, Jiulongpo Chongqing, CN;
Xiang Mei, Jiulongpo Chongqing, CN;
Chunlan HU, Jiulongpo Chongqing, CN;
Kai Fan, Jiulongpo Chongqing, CN;
Chun Zhang, Jiulongpo Chongqing, CN;
Xuefeng Ma, Jiulongpo Chongqing, CN;
Xiang Mei, Jiulongpo Chongqing, CN;
Chunlan Hu, Jiulongpo Chongqing, CN;
Chongqing Fagen Biomedical Inc., Jiulongpo Chongqing, CN;
Abstract
The present invention provides a humanized recombinant uricase and mutants thereof, wherein the humanized recombinant uricase is a chimeric protein which comprises amino acids of non-human mammal uricase and amino acids of human uricase. The humanized recombinant unease and mutants thereof have reduced immunogenicity in human, and can be used for the treatment of hyperuricemia and gout.