The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 19, 2013
Filed:
Apr. 26, 2007
Robson Augusto Souza Dos Santos, Belo Horizonte, BR;
Sergio Henrique Sousa Santos, Belo Horizonte, BR;
Jaqueline Isaura Alvarez Leite, Belo Horizonte, BR;
Marina Matos DE Moura, Belo Horizonte, BR;
Andrea Siqueira Haibara, Belo Horizonte, BR;
Luciana Rodriques Fernandez, Belo Horizonte, BR;
Michael Bader, Berlin, DE;
Natalia Alenina, Berlin, DE;
Rubens Dario Sinisterra, Belo Horizonte, BR;
Robson Augusto Souza Dos Santos, Belo Horizonte, BR;
Sergio Henrique Sousa Santos, Belo Horizonte, BR;
Jaqueline Isaura Alvarez Leite, Belo Horizonte, BR;
Marina Matos De Moura, Belo Horizonte, BR;
Andrea Siqueira Haibara, Belo Horizonte, BR;
Luciana Rodriques Fernandez, Belo Horizonte, BR;
Michael Bader, Berlin, DE;
Natalia Alenina, Berlin, DE;
Rubens Dario Sinisterra, Belo Horizonte, BR;
Max-Delbruck-Centrum fur Molekulare Medizin, Berlin, DE;
Universidade Federal de Minas Gerais, Belo Horizonte, BR;
Abstract
The present invention is characterized by the use of Mas-G-protein-coupled receptor agonists for the control, prevention and treatment of the body levels of triglycerides, cholesterol and glucose, as well as of hyper-tension and possible increase in body weight, which are characteristic of the clinical manifestation of the metabolic syndrome and its complications. Another characteristic of the invention is the use of Mas-G-protein-coupled receptor agonists, including the Angiotensin-(1-7) peptide and its analogs, agonists, either peptidic or non-peptidic, as modulators of the manifestations of insulin resistance and glucose intolerance and in the prevention and treatment of the related alterations. The invention claims the use of MAS-G-protein-coupled receptor agonists, formulated with pharmaceutically and pharmacologically acceptable excipients or carriers, and Mas-G-protein-coupled receptor agonists, including the Angiotensin-(1-7) peptide and its analogs, agonists, either peptidic or non-peptidic, as modulators of the metabolic syndrome, the diseases that compose it and its complications.