The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2013
Filed:
Mar. 30, 2010
Norihiko Watanabe, Chiba, JP;
Yoshihiro Oya, Chiba, JP;
Norihiko Watanabe, Chiba, JP;
Yoshihiro Oya, Chiba, JP;
National University Corporation Chiba University, Chiba, JP;
Abstract
A method of identifying a compound for preventing and/or treating an autoimmune disease is described which comprises obtaining a (BTLA) NKT cell from a non-human animal, contacting the (BTLA) NKT cell ex vivo with a test compound, in the presence of an antigen, measuring a response of the (BTLA) NKT cell to the antigen, comparing the response of the (BTLA) NKT cell to the antigen with a response of a (BTLA) NKT cell in control assay, and selecting the compound that reduces the response of the (BTLA) NKT cell in the presence of an antigen compared to a response of a (BTLA) NKT cell in the control assay. Other methods of identifying a compound for preventing and/or treating an autoimmune disease are also described.