The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2013

Filed:

Sep. 01, 2009
Applicants:

Piet Tom Bert Paul Wigerinck, Terhagen, BE;

Dominique Louis Nestor Ghislain Surleraux, Braine-le-château, BE;

Wim Gaston Verschueren, Berchem, BE;

Herman Augustinus DE Kock, Arendonk, BE;

Wim Albert Alex Aelterman, Gierle, BE;

Inventors:
Assignee:

Janssen R&D Ireland, Little Island, Co, Cork, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 493/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a process for the preparation of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate as well as novel intermediates for use in said process. (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate is particularly useful as an HIV protease inhibitor.


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