The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2013

Filed:

Aug. 20, 2012
Applicants:

William M. Winston, Jr., Marlborough, MA (US);

S. Kirk Wright, Waltham, MA (US);

May Han, Brookline, MA (US);

Lyne Breault, Roslindale, MA (US);

Jie Lin, West Roxbury, MA (US);

Bijan Etemad-gilbertson, Jamaica Plain, MA (US);

Christine Knuehl, Natick, MA (US);

Jeno Gyuris, Lincoln, MA (US);

Arnold Horwitz, San Leandro, CA (US);

Inventors:

William M. Winston, Jr., Marlborough, MA (US);

S. Kirk Wright, Waltham, MA (US);

May Han, Brookline, MA (US);

Lyne Breault, Roslindale, MA (US);

Jie Lin, West Roxbury, MA (US);

Bijan Etemad-Gilbertson, Jamaica Plain, MA (US);

Christine Knuehl, Natick, MA (US);

Jeno Gyuris, Lincoln, MA (US);

Arnold Horwitz, San Leandro, CA (US);

Assignee:

AVEO Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF. The binding proteins can be used as diagnostic and/or therapeutic agents. With regard to their therapeutic activity, the binding proteins can be used to treat certain HGF responsive disorders, for example, certain HGF responsive tumors.


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