The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2013
Filed:
Dec. 15, 2005
Reiji Kannagi, Nagoya, JP;
Mineko Izawa, Seto, JP;
Naoko Kimura, Nagoya, JP;
Shunsuke Kurei, Nagano, JP;
Kazue Watanabe, Nagano, JP;
Reiji Kannagi, Nagoya, JP;
Mineko Izawa, Seto, JP;
Naoko Kimura, Nagoya, JP;
Shunsuke Kurei, Nagano, JP;
Kazue Watanabe, Nagano, JP;
Japan Science and Technology Agency, Saitama, JP;
Local Government of Aichi Prefecture, Aichi, JP;
Wako Pure Chemical Industries, Ltd., Osaka, JP;
Abstract
[PROBLEMS] To provide examination methods and reagents able to detect efficiently cancer patients and patients at high risk of cancer. [MEANS FOR SOLVING PROBLEMS] Significant differences in the distribution of GlcNAc-6-sulfotransferase isozymes, sulfation enzymes of sugar residues, between non-carcinoma tissues and carcinoma tissues or adenoma tissues were discovered. The discovery is evidently applicable to detect carcinomas and adenomas (except colorectal carcinomas and colorectal adenomas) specifically by assaying a certain range of GlcNAc-6-sulfated sugar residue groups in tissues of patients and in fecal samples. Examination of carcinomas and adenomas is possible by the use of antibodies reacting specifically with GlcNAc-6-sulfated sugar residues specifically synthesized by enzymes present in carcinoma and adenoma tissues.