The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2013

Filed:

Dec. 20, 2006
Applicants:

Roger Smith, Chester Springs, PA (US);

Jacques Dumas, Carlisle, MA (US);

Gan Wang, Wallingford, CT (US);

Wendy Lee, San Ramon, CA (US);

Karl Miranda, Lexington, MA (US);

Inventors:

Roger Smith, Chester Springs, PA (US);

Jacques Dumas, Carlisle, MA (US);

Gan Wang, Wallingford, CT (US);

Wendy Lee, San Ramon, CA (US);

Karl Miranda, Lexington, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
Abstract

Substituted pyrimidine derivatives of formula (I), salts, metabolites, prodrugs and diastereoisomeric forms (both isolated stereoisomers and mixtures of stereoisomers) thereof (wherein A=pyrimidine) pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with other active ingredients, e.g., cytotoxic therapies.


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