The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2013

Filed:

Sep. 03, 2010
Applicants:

Elena Casale, Somma Lombardo, IT;

Francesco Casuscelli, Dairago, IT;

Claudio Dalvit, Milan, IT;

Paolo Polucci, Cassina Rizzardi, IT;

Fabio Zuccotto, Milan, IT;

Inventors:

Elena Casale, Somma Lombardo, IT;

Francesco Casuscelli, Dairago, IT;

Claudio Dalvit, Milan, IT;

Paolo Polucci, Cassina Rizzardi, IT;

Fabio Zuccotto, Milan, IT;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/5377 (2006.01); C12N 9/99 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to [1,2,4]triazolo[1,5-c]pyrimidine derivatives of formula (I) which inhibit the activity of Heat Shock Protein Hsp90. The compounds of the invention are therefore useful in treating proliferative diseases such as cancer and neurodegenerative diseases. The present invention also provides processes for preparing these compounds, methods of treating diseases and the pharmaceutical compositions comprising these compounds.


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