The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2013

Filed:

Dec. 02, 2011
Applicants:

Edward James Olhava, Newton, MA (US);

Richard Chesworth, Boston, MA (US);

Kevin Wayne Kuntz, Woburn, MA (US);

Victoria M. Richon, Wellesley, MA (US);

Roy Macfarlane Pollock, Medford, MA (US);

Scott Richard Daigle, Newburyport, MA (US);

Inventors:

Edward James Olhava, Newton, MA (US);

Richard Chesworth, Boston, MA (US);

Kevin Wayne Kuntz, Woburn, MA (US);

Victoria M. Richon, Wellesley, MA (US);

Roy Macfarlane Pollock, Medford, MA (US);

Scott Richard Daigle, Newburyport, MA (US);

Assignee:

Epizyme, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 19/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to substituted purine and 7-deazapurine compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating disorders in which DOT1-mediated protein methylation plays a part, such as cancer and neurological disorders, by administering these compounds and pharmaceutical compositions to subjects in need thereof.


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