The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2013
Filed:
Mar. 19, 2008
Applicants:
Jens BO Rode Hansen, Charlottelund, DK;
Henrik Orum, Værløse, DK;
Henrik Frydenlund Hansen, Rødovre, DK;
Ellen Marie Straarup, Birkerød, DK;
Niels Fisker Nielsen, Kgs. Lyngby, DK;
Maj Hedtjärn, København, DK;
Inventors:
Jens Bo Rode Hansen, Charlottelund, DK;
Henrik Orum, Værløse, DK;
Henrik Frydenlund Hansen, Rødovre, DK;
Ellen Marie Straarup, Birkerød, DK;
Niels Fisker Nielsen, Kgs. Lyngby, DK;
Maj Hedtjärn, København, DK;
Assignee:
Santaris Pharma A/S, Horsholm, DK;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C07H 21/04 (2006.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides LNA gapmer oligomers of between 10-20 nucleobases in length, which have a total of 1-3 phosphodiester internucleoside linkages. Such oligomers have been found to have superior bioavailability and have also been found to selectively accumulate in kidney cells.