The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2013
Filed:
Aug. 22, 2012
Applicants:
Nozomu Nishi, Kagawa, JP;
Mitsuomi Hirashima, Kagawa, JP;
Akira Yamauchi, Kagawa, JP;
Aiko Ito, Kagawa, JP;
Inventors:
Nozomu Nishi, Kagawa, JP;
Mitsuomi Hirashima, Kagawa, JP;
Akira Yamauchi, Kagawa, JP;
Aiko Ito, Kagawa, JP;
Assignee:
Galpharma Co., Ltd., Kagawa, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 35/02 (2006.01); A61K 35/04 (2006.01); C07K 14/00 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
A recombinant galectin 9 (rGal 9) is provided which exhibits an immune system-mediated action and a direct action on tumor cells (i.e., activity of inducing the intercellular adhesion and apoptosis of the tumor cells), thereby potent in inducing the inhibition of cancer metastasis and reduction. Moreover, the rGal 9 exerts no efficacy on non-activated lymphocytes but can induce apoptosis in activated T cells, in particular, CD4-positive T cells causing an excessive immune response.