The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 12, 2013

Filed:

Sep. 14, 2009
Applicants:

Julia Sidenius Johansen, Frederiksberg, DK;

Nicolai Aagaard Schultz, Frederiksberg, DK;

Benny Vittrup Jensen, Roskilde, DK;

Stig Bojesen, København Ø, DK;

Børge Grønne Nordestgaard, Genrofte, DK;

Hans Jørgen Nielsen, Kongens Lyngby, DK;

Ib Jarle Christensen, Hillerød, DK;

Inventors:

Julia Sidenius Johansen, Frederiksberg, DK;

Nicolai Aagaard Schultz, Frederiksberg, DK;

Benny Vittrup Jensen, Roskilde, DK;

Stig Bojesen, København Ø, DK;

Børge Grønne Nordestgaard, Genrofte, DK;

Hans Jørgen Nielsen, Kongens Lyngby, DK;

Ib Jarle Christensen, Hillerød, DK;

Assignees:

Herlev Hospital, Herlev, DK;

Rigshospitalet, Kobenhavn O, DK;

Hvidovre Hospital, Hvidovre, DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to gastrointestinal cancers and methods for selecting a treatment for said gastrointestinal cancer in a subject. The present invention further relates to a methods of diagnosing the presence of and/or classifying the severity of a gastrointestinal cancer; together with methods for determining the effect of a therapy administered and/or the prognosis for a subject suffering from a gastrointestinal cancer, before, during or after administering the treatment. For all the methods applies that a determined level of YKL-40 above one or more reference levels indicates the treatment, the severity of the disease, the effect of the treatment and/or the prognosis of the subject. The reference level is typically a level obtained from healthy individuals or a level previously obtained from the same subject. The subject may suffer from any one or more gastrointestinal cancers, such as upper gastrointestinal cancers, and metastatic colorectal cancer. The present invention further relates to a kit and a device that may be used in the method of the present invention.


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