The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2013
Filed:
Sep. 12, 2011
Applicants:
Melanie Ott, Mill Valley, CA (US);
Sara Pagans Lista, San Francisco, CA (US);
Inventors:
Melanie Ott, Mill Valley, CA (US);
Sara Pagans Lista, San Francisco, CA (US);
Assignee:
The J. David Gladstone Institutes, San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); G01N 33/53 (2006.01); A61K 39/21 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides isolated methylated Tat peptides; and compositions comprising the peptides. The present invention further provides isolated antibodies specific for a Lys-51-methylated Tat polypeptide. Also provided are methods of identifying agents that inhibit Lys-51 methylation of a Tat polypeptide. The present invention further provides methods of treating an immunodeficiency virus infection in a mammalian subject.