The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2013
Filed:
Oct. 29, 2010
Joseph M. Metzger, Ann Arbor, MI (US);
Dewayne Townsend, Ann Arbor, MI (US);
Soichiro Yasuda, Ann Arbor, MI (US);
Daniel E. Michele, Ann Arbor, MI (US);
Joseph M. Metzger, Ann Arbor, MI (US);
Dewayne Townsend, Ann Arbor, MI (US);
Soichiro Yasuda, Ann Arbor, MI (US);
Daniel E. Michele, Ann Arbor, MI (US);
The Regents of the University of Michigan, Ann Arbor, MI (US);
Abstract
The present invention relates to compositions and methods for treating and preventing heart disease. In particular, the present invention provides compositions comprising poloxamers (e.g., poloxamer 188-P188) and methods of using the same for treating and preventing heart disease (e.g., in subjects with muscular dystrophy) and for treating cells and tissue damage caused by ischemia and cell death (e.g., for treating dystrophin-deficient cells (e.g., myocytes)).