The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 12, 2013
Filed:
Feb. 23, 2010
Songping D. Huang, Kent, OH (US);
Soumitra Basu, Kent, OH (US);
Anatoly K. Khitrin, Kent, OH (US);
Mohammadreza Shokouhimehr, Kent, OH (US);
Eric Scott Soehnlen, Kent, OH (US);
Songping D. Huang, Kent, OH (US);
Soumitra Basu, Kent, OH (US);
Anatoly K. Khitrin, Kent, OH (US);
Mohammadreza Shokouhimehr, Kent, OH (US);
Eric Scott Soehnlen, Kent, OH (US);
Kent State University, Kent, OH (US);
Abstract
A material useful as a MRI contrast agent used for medical imaging, drug delivery platform or other functions are provided as a class of non-gadolinium and non-iron oxide based materials that comprise Prussian blue materials or analogue materials. The materials may be used as T-weighted and/or T-weighted MRI contrast agents for imaging, including cellular imaging, in clinical diagnosis and biomedical research applications. The agent is a compound created from Prussian blue materials that is non-toxic, and can be internalized by cells through endocytosis. The Prussian blue materials may also be used for drug delivery applications. The Prussian blue materials may be administered orally to a subject in either medical imaging or drug delivery applications or dual modality MRI-Fluorescence imaging agent.