The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2013
Filed:
Dec. 12, 2008
Michael G. Palmgren, Gentorfte, DK;
Morten Buch-pedersen, Copenhagen, DK;
Bjørn Pañella Pedersen, Aarhus, DK;
Poul Nissen, Risskov, DK;
Michael G. Palmgren, Gentorfte, DK;
Morten Buch-Pedersen, Copenhagen, DK;
Bjørn Pañella Pedersen, Aarhus, DK;
Poul Nissen, Risskov, DK;
Aarhus Universitet, Aarhus C, DK;
Kobenhavns Universitet, Kobenhaven K, DK;
Abstract
The present invention relates to a crystal structure of a plasma membrane proton pump type ATPase. The invention further describes method for identification of modulators of ATPases as well as uses of such modulators. Based on the provided three dimensional structure of the ATPase, various method, such as computer implemented methods may be used for identification of modulators, such putative modulators may be further analysed using in vitro and in vivo experiments to confirm there functionality. Several modulator interaction regions are described as target of regulation by ATPase modulators.