The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2013
Filed:
May. 27, 2009
Chris Sander, Cambridge, MA (US);
Sven Nelander, Gothenburg, SE;
Wei Qing Wang, Jersey City, NJ (US);
Peter Gennemark, Kungsbacka, SE;
Björn Nilsson, Lund, SE;
Chris Sander, Cambridge, MA (US);
Sven Nelander, Gothenburg, SE;
Wei Qing Wang, Jersey City, NJ (US);
Peter Gennemark, Kungsbacka, SE;
Björn Nilsson, Lund, SE;
Sloan Kettering Institute for Cancer Research, New York, NY (US);
Abstract
Techniques for modeling living biological systems include receiving constant values for multiple interaction factors w. A set of initial state values is received for state variables that indicate relevant properties of a living biological system. Also received is a set of trial values for perturbation variables that indicate factors that might affect one or more of the relevant properties of the biological system. A temporal change in a value for a particular state variable is determined based on a non-linear transformation of a sum of the trial value for the perturbation that affects the particular state added to a sum of all non-zero values for a product of wand a state variable over all state variables. In some embodiments, measurement-based values are received for a measurable subset of the state variables. Values for the constant interaction factors ware determined based on the measurement-based values.