The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2013
Filed:
Oct. 17, 2012
Nof Corporation, Tokyo, JP;
Fumiaki Manabe, Kawasaki, JP;
Yuji Yamamoto, Kawasaki, JP;
NOF Corporation, Tokyo, JP;
Abstract
Provided is a polyethylene glycol derivative which contains two PEG chains, which is bound to a diacylglycerol, which has high purity, and which enhances the stability of liposomes. Polyethylene glycol is represented by the following formula (1) and which is bound to a diacylglycerol: In Formula (1), Ris a hydrocarbon group containing 1 to 7 carbon atoms, Ris an alkyl or alkenyl group containing 9 to 21 carbon atoms, n is the average number of moles of added polyethylene glycol chains, 10≦n≦100, and X is a linker site between branched polyethylene glycol and the diacylglycerol and is represented by the following formula (2):—(CH)-Y—(CH)-  (2)In Formula (2), Y is an ether bond, an ester bond, a urethane bond, an amide bond, or a carbonate bond and l and m are an integer of 0 to 6.