The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8575330 B1

PDF
Full Text
Expired
Date of Patent:
Nov. 05, 2013

Filed:

Jul. 10, 2012
Applicant:

Ping-heng Tan, Kaohsiung, TW;

Inventor:

Ping-Heng Tan, Kaohsiung, TW;

Assignee:

I-Shou University, Kaohsiung, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a microRNA-based short hairpin RNA for gene silencing the genetic expression of NR1 subunit of N-methyl-D-aspartate receptor comprises a single strand RNA fragment comprising a first fragment, a second fragment and a connecting fragment, wherein the first fragment and the second fragment are complementary to each other, and are spaced and connected by the connecting fragment, with the connecting fragment being randomly arranged nucleotides, with the first fragment having a Drosha recognized cleavage site, a silencing site and a Dicer recognized cleavage site, with the Drosha recognized cleavage site and the Dicer recognized cleavage site being spaced and connected by the silencing site, with the silencing site encoding homologous nucleotides corresponding to NR1 subunit of subcutaneous N-methyl-D-aspartate receptor.


Find Patent Forward Citations

Tan, Ping-Heng. (2013). Microrna-based short hairpin rna for gene knockdown of nr1 subunit of n-methyl-d-aspartate receptor and its application on pharmaceutics (U.S. Patent No. 8575330). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8575330

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…