The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2013
Filed:
Mar. 09, 2010
Christian Hackenberger, Berlin, DE;
Giuseppe Del Signore, Nijmegen, NL;
Remigiusz Serwa, Berlin, DE;
Ina Wilkening, Berlin, DE;
Robert Vallee, Berlin, DE;
Christian Hackenberger, Berlin, DE;
Giuseppe Del Signore, Nijmegen, NL;
Remigiusz Serwa, Berlin, DE;
Ina Wilkening, Berlin, DE;
Robert Vallee, Berlin, DE;
Freie Universitaet Berlin, Berlin, DE;
Abstract
A modified compound that has at least one further functional group, in particular a bio- or macromolecule, comprising at least one x-fold (x≧1) chemoselectively incorporated phosphoramidate group of general formula (I), NPO(OR)(OR), and/or at least one x-fold (x≧1) chemoselectively incorporated phosphonamide group of general formula (Ia), NPO(R)(OR). Rand Ris selected from the group containing glycerol, polyglycerol, PEG polymers of the general empirical formula CHOwith n≧1, C-alkyl chains with n≧1; functionalized C-alkyl chains with n≧1, aryls, heteroaryl, silyl, lipids, fluorophores, saccharides, peptides, crown ethers, or a linker, which links the aforementioned groups. Rand Rcan be identical to or different from one another.