The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 05, 2013
Filed:
Jun. 16, 2010
Xiaohong Cai, Redwood City, CA (US);
Jian-xin Duan, Redwood City, CA (US);
Mark Matteucci, Redwood City, CA (US);
Yeyu Cao, Redwood City, CA (US);
Hailong Jiao, Redwood City, CA (US);
Xiaohong Cai, Redwood City, CA (US);
Jian-Xin Duan, Redwood City, CA (US);
Mark Matteucci, Redwood City, CA (US);
Yeyu Cao, Redwood City, CA (US);
Hailong Jiao, Redwood City, CA (US);
Threshold Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
Various 14-nitro, 14-amino, and 14-substituted amino camptothecin derivatives are useful in the treatment of cancer and other hyperproliferative diseases. 14-Nitro camptothecin derivatives are conveniently prepared by reacting a camptothecin derivative with fuming nitric acid, optionally employing acetic anhydride as a solvent.