The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2013

Filed:

Dec. 07, 2009
Applicants:

Christian Fischer, Natick, MA (US);

Joey Methot, Westwood, MA (US);

Hua Zhou, Acton, MA (US);

Adam J. Schell, Newton, MA (US);

Benito Munoz, Cambridge, MA (US);

Alexey A. Rivkin, Boston, MA (US);

Sean P. Ahearn, Somerville, MA (US);

Stephanie Chichetti, Brooklyn, NY (US);

Rachel N. Maccoss, Brookline, MA (US);

Sam Kattar, Arlington, MA (US);

Matthew Christopher, Brookline, MA (US);

Chaomin LI, Boston, MA (US);

Andrew Rosenau, Cambridge, MA (US);

William Colby Brown, Cleveland Heights, OH (US);

Inventors:

Christian Fischer, Natick, MA (US);

Joey Methot, Westwood, MA (US);

Hua Zhou, Acton, MA (US);

Adam J. Schell, Newton, MA (US);

Benito Munoz, Cambridge, MA (US);

Alexey A. Rivkin, Boston, MA (US);

Sean P. Ahearn, Somerville, MA (US);

Stephanie Chichetti, Brooklyn, NY (US);

Rachel N. MacCoss, Brookline, MA (US);

Sam Kattar, Arlington, MA (US);

Matthew Christopher, Brookline, MA (US);

Chaomin Li, Boston, MA (US);

Andrew Rosenau, Cambridge, MA (US);

William Colby Brown, Cleveland Heights, OH (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/14 (2006.01); A61K 31/4196 (2006.01);
U.S. Cl.
CPC ...
Abstract

According to the invention there is provided a compound of formula I or a pharmaceutically acceptable salt or hydrate thereof; wherein the variables are as defined herein. The compounds selectively attenuate the production of Aβ42 and hence are useful in treatment of Alzheimer's disease and related conditions.


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