The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2013

Filed:

Oct. 30, 2008
Applicants:

Nadia Dahmane, Philadelphia, PA (US);

Jeffrey D. Winkler, Wynnewood, PA (US);

Inventors:

Nadia Dahmane, Philadelphia, PA (US);

Jeffrey D. Winkler, Wynnewood, PA (US);

Assignees:

The Wistar Institute, Philadelphia, PA (US);

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to steroid-derived cyclopamine analogs and methods for using the same for inhibiting sonic hedgehog signaling and preventing or treating cancer. A method for synthesizing the analogs of the present invention from a steroid is also provided.


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