The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2013

Filed:

Oct. 21, 2008
Applicants:

Curtis C. Harris, Bethesda, MD (US);

Kaori Fujita, Bethesda, MD (US);

Izumi Horikawa, Bethesda, MD (US);

Borivoj Vojtesek, Brno, CZ;

Jean-christophe Bourdon, Dundee, GB;

David P. Lane, Dundee, GB;

Inventors:

Curtis C. Harris, Bethesda, MD (US);

Kaori Fujita, Bethesda, MD (US);

Izumi Horikawa, Bethesda, MD (US);

Borivoj Vojtesek, Brno, CZ;

Jean-Christophe Bourdon, Dundee, GB;

David P. Lane, Dundee, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.


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