The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2013

Filed:

Aug. 28, 2008
Applicants:

Paul Steven Wright, New Hope, PA (US);

Paul Weissensee, Andover, NJ (US);

Haifeng Eishingdrelo, Montville, NJ (US);

Jidong Cai, Bedminster, NJ (US);

Inventors:

Paul Steven Wright, New Hope, PA (US);

Paul Weissensee, Andover, NJ (US);

Haifeng Eishingdrelo, Montville, NJ (US);

Jidong Cai, Bedminster, NJ (US);

Assignee:

Sanofi, Paris, FR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/37 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods and assays for identifying a compound that modulates a protein-protein interaction between a first and a second protein. The methods and assays require a protease that is attached to the second protein and a split and rearranged reporter activating protein that is attached to the first protein, wherein the reporter activating protein comprises a cleavage site for the protease that is interposed between two portions of the reporter activating protein and wherein the two portions of the reporter activating protein are in a rearranged order.


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