The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2013

Filed:

Jan. 27, 2012
Applicants:

Nick Vandeghinste, Duffel, BE;

Peter Herwig Maria Tomme, Gent, BE;

Frits Michiels, Leiderdorp, NL;

Libin MA, Oegstgeest, NL;

Blandine Mille-baker, Oegstgeest, NL;

Helmuth G. G. Van ES, Haarlem, NL;

Inventors:

Nick Vandeghinste, Duffel, BE;

Peter Herwig Maria Tomme, Gent, BE;

Frits Michiels, Leiderdorp, NL;

Libin Ma, Oegstgeest, NL;

Blandine Mille-Baker, Oegstgeest, NL;

Helmuth G. G. van Es, Haarlem, NL;

Assignee:

Galapagos N.V., Mechelen, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inducing anabolic stimulation of chondrocytes, including cartilage formation enhancing pharmaceutical compositions, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean cartilage thickness in a subject.


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