The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2013

Filed:

Jul. 18, 2012
Applicants:

Juan A. Vergez, Buenos Aires, AR;

Joaquina Faour, Buenos Aires, AR;

Ana C. Pastini, Buenos Aires, AR;

Guido S. Bigatti, Buenos Aires, AR;

Glenn A. Meyer, Wilmington, NC (US);

Ethel C. Feleder, Buenos Aires, AR;

Marcelo A. Ricci, Buenos Aires, AR;

Marcelo A. Coppari, Buenos Aires, AR;

Marcelo F. Befumo, Buenos Aires, AR;

Inventors:

Juan A. Vergez, Buenos Aires, AR;

Joaquina Faour, Buenos Aires, AR;

Ana C. Pastini, Buenos Aires, AR;

Guido S. Bigatti, Buenos Aires, AR;

Glenn A. Meyer, Wilmington, NC (US);

Ethel C. Feleder, Buenos Aires, AR;

Marcelo A. Ricci, Buenos Aires, AR;

Marcelo A. Coppari, Buenos Aires, AR;

Marcelo F. Befumo, Buenos Aires, AR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/24 (2006.01);
U.S. Cl.
CPC ...
Abstract

The osmotic devices of the present invention contain a unitary core comprising a salt of amantadine and an osmotic salt, wherein the two salts have an ion in common. The release rate of the amantadine is a sigmoidal release. The osmotic device includes a semipermeable membrane having a controlled porosity that can be adapted as needed to cooperate with the osmotic salt in providing a predetermined drug release profile. The osmotic salt need not be coated and it is in admixture with the amantadine salt. The osmotic device further includes a drug-containing coat external to the semipermeable membrane. The osmotic device can include one or more additional drugs in the core and/or the drug-containing coat.


Find Patent Forward Citations

Loading…