The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2013

Filed:

Jul. 24, 2008
Applicants:

David Perrin, Vancouver, CA;

Richard Ting, Vancouver, CA;

Christopher Overall, Vancouver, CA;

Inventors:

David Perrin, Vancouver, CA;

Richard Ting, Vancouver, CA;

Christopher Overall, Vancouver, CA;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Substituted aryl-boron compounds comprising at least oneF atom, as illustrated by the formula (I), where at least one of Yor YisF and Ais a substituted aromatic ring, with Gbeing, independently, C or N, and where the substitutents of the aromatic ring or polycyclic moiety (other than boron) comprise at least one electron-withdrawing group (EWG), providing that sigma total (σ) for all substituents on the aromatic ring or polycyclic moiety except B is about 0.06 or more when said at least one EWG is positioned ortho to B, or about 0.2 or more when no EWG is positioned ortho to B. The compounds include neutral (N=1) and ionic borate (N=2) embodiments. The compounds are useful as positron emission tomography (PET) imaging agents.


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