The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 05, 2013

Filed:

Dec. 21, 2012
Applicants:

Hsing-wen Sung, Hsinchu, TW;

Ha Giang Thi Nguyen, Hsinchu, TW;

Fang Yi Su, Hsinchu, TW;

Er-yuan Chuang, Hsinchu, TW;

Zi-xian Liao, Hsinchu, TW;

Hosheng Tu, Newport Beach, CA (US);

Inventors:

Hsing-Wen Sung, Hsinchu, TW;

Ha Giang Thi Nguyen, Hsinchu, TW;

Fang Yi Su, Hsinchu, TW;

Er-Yuan Chuang, Hsinchu, TW;

Zi-Xian Liao, Hsinchu, TW;

Hosheng Tu, Newport Beach, CA (US);

Assignees:

GP Medical, Inc., Newport Beach, CA (US);

National Tsing Hua University, Hsinchu, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention discloses a pharmaceutical composition of nanoparticles consisting of chitosan, a negatively charged substrate, and at least one bioactive agent that is encapsulated within cucurbiturils for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.


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