The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2013
Filed:
Oct. 17, 2008
Diógenes Quintana Vázquez, Ciudad de la Habana, CU;
Tamara Menendez Medina, Ciudad Habana, CU;
Anabel Álvarez Acosta, Ciudad de la Habana, CU;
Yoelys Cruz Leal, Ciudad de la Habana, CU;
Gerardo Enrique Guillen Nieto, Ciudad de la Habana, CU;
Diógenes Quintana Vázquez, Ciudad de la Habana, CU;
Tamara Menendez Medina, Ciudad Habana, CU;
Anabel Álvarez Acosta, Ciudad de la Habana, CU;
Yoelys Cruz Leal, Ciudad de la Habana, CU;
Gerardo Enrique Guillen Nieto, Ciudad de la Habana, CU;
Centro de Ingenieria Genetica y Biotecnologia, La Habana, CU;
Abstract
The present invention is related with the field of Biomedicine. It comprises the engineering of the Pertactin protein (Prn) and using it as part of bacterial vaccines, and more precisely, as part of acellular vaccines against. The engineered Prn molecules comprise on their structure polimorfisms from differentstrains, and induce immune responses with protective capacity and opsonophagocytic activity when assayed as vaccines, higher than that generated by other pre-existing vaccines. The engineered Prn variants of the present invention are applicable in human and veterinary medicine.