The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2013

Filed:

Apr. 30, 2010
Applicants:

Damian O Arnaiz, El Sobrante, CA (US);

Greg Brown, Oakland, CA (US);

Emmanuel Claret, Besancon, FR;

Arwed Cleve, Berlin, GR;

David Davey, El Sobrante, CA (US);

William Guilford, Belmont, CA (US);

Seock-kyu Khim, Orinda, CA (US);

Thomas Kirkland, Atascadero, CA (US);

Monica J Kochanny, Benicia, CA (US);

Amy Liang, Vallejo, CA (US);

David Light, San Mateo, CA (US);

John Parkinson, Martinez, CA (US);

David Vogel, Richmond, CA (US);

Guo Ping Wei, San Ramon, CA (US);

Bin YE, Moraga, CA (US);

Inventors:

Damian O Arnaiz, El Sobrante, CA (US);

Greg Brown, Oakland, CA (US);

Emmanuel Claret, Besancon, FR;

Arwed Cleve, Berlin, GR;

David Davey, El Sobrante, CA (US);

William Guilford, Belmont, CA (US);

Seock-Kyu Khim, Orinda, CA (US);

Thomas Kirkland, Atascadero, CA (US);

Monica J Kochanny, Benicia, CA (US);

Amy Liang, Vallejo, CA (US);

David Light, San Mateo, CA (US);

John Parkinson, Martinez, CA (US);

David Vogel, Richmond, CA (US);

Guo Ping Wei, San Ramon, CA (US);

Bin Ye, Moraga, CA (US);

Assignee:

Celtaxsys, Inc., Atlanta, GA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01); C07D 241/36 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention is directed to compounds of formula (I): where r, q, R, R, R, R, R, R, R, R, R, R, R, R, and Rare described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene Ahydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.


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