The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2013
Filed:
Mar. 14, 2007
Kenji Fukunaga, Kanagawa, JP;
Toshiyuki Kohara, Kanagawa, JP;
Kazutoshi Watanabe, Kanagawa, JP;
Yoshihiro Usui, Ibaraki, JP;
Fumiaki Uehara, Kanagawa, JP;
Satoshi Yokoshima, Tokyo, JP;
Daiki Sakai, Cambridge, GB;
Shin-ichi Kusaka, Kanagawa, JP;
Kazuki Nakayama, Kanagawa, JP;
Kenji Fukunaga, Kanagawa, JP;
Toshiyuki Kohara, Kanagawa, JP;
Kazutoshi Watanabe, Kanagawa, JP;
Yoshihiro Usui, Ibaraki, JP;
Fumiaki Uehara, Kanagawa, JP;
Satoshi Yokoshima, Tokyo, JP;
Daiki Sakai, Cambridge, GB;
Shin-ichi Kusaka, Kanagawa, JP;
Kazuki Nakayama, Kanagawa, JP;
Mitsubishi Tanabe Pharma Corporation, Osaka, JP;
Sanofi, Paris, FR;
Abstract
A compound represented by the formula (I), an optically active isomer thereof, or a pharmaceutical acceptable salt thereof: wherein Rrepresents a hydrogen or the like; Rrepresents methyl group or the like; Rrepresents a halogen atom or the like; q represents an integer of 0 to 3; Z represent nitrogen atom, CH, or the like; Rrepresents hydrogen or the like; Rrepresents hydrogen or the like; Rrepresents a substituted alkyloxy and the like; p represents an integer of 0 to 3; X represents bond, CH, oxygen atom, NH, or the like; any one or more of Rand R, Rand R, Rand R, X and R, X and R, X and R, and Rand Rmay combine to each other to form a ring, which is used for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity such as a neurodegenerative diseases (e.g. Alzheimer disease).