The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2013

Filed:

Oct. 29, 2009
Applicants:

Herman Kempen, Dornach, CH;

Daniel Bellus, Riehen, CH;

Barbara Staehelin, Binningen, CH;

Inventors:

Herman Kempen, Dornach, CH;

Daniel Bellus, Riehen, CH;

Barbara Staehelin, Binningen, CH;

Assignee:

CircoMed LLC, Parsippany, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 9/00 (2006.01); A61K 31/551 (2006.01); C07D 495/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to new thienotriazolodiazepine derivatives of the formula (1) wherein Ris CH, Ris CHor —(CH)—Ror —(CH)—O—Ror —(CH)—S—Rwherein n is 1, 2, 3 or 4 and Ris CH, CHCHor CHCHOCH, and Ris hydrogen or —OCHO— or —OCHCHO— connected to the ortho/meta position or meta/para position of the phenyl ring; or wherein Rand Rare hydrogen and Ris —OCHO— Or —OCHCHO— connected to the ortho/meta position or meta/para position of the phenyl ring; and pharmaceutically acceptable acid addition salts thereof. These compounds and pharmaceutical compositions containing them are useful in the treatment and prevention of atherosclerotic artery diseases, such as myocardial infarction and stroke, and of Alzheimer's disease.


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