The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2013

Filed:

Dec. 11, 2008
Applicants:

Efrat Ben-zeev, K. Motzkin, IL;

Dongli Chen, Brighton, MA (US);

Merav Fichman, Modi'in, IL;

Shomir Ghosh, Brookline, MA (US);

Steffi Koerner, Medford, MA (US);

Jian Lin, Acton, MA (US);

Yael Marantz, Kadima, IL;

Rosa E. Melendez, Toronto, CA;

Pradyumna Mohanty, Woburn, MA (US);

Sharon Shacham, Chestnut Hill, MA (US);

Zhaoda Zhang, Andover, MA (US);

Inventors:

Efrat Ben-Zeev, K. Motzkin, IL;

Dongli Chen, Brighton, MA (US);

Merav Fichman, Modi'in, IL;

Shomir Ghosh, Brookline, MA (US);

Steffi Koerner, Medford, MA (US);

Jian Lin, Acton, MA (US);

Yael Marantz, Kadima, IL;

Rosa E. Melendez, Toronto, CA;

Pradyumna Mohanty, Woburn, MA (US);

Sharon Shacham, Chestnut Hill, MA (US);

Zhaoda Zhang, Andover, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/4375 (2006.01);
U.S. Cl.
CPC ...
Abstract

Chemokine receptor antagonists, in particular, compounds of Formula (I-A) that act as antagonists of the chemokine CCR2 receptor, including pharmaceutical compositions and uses thereof to treat or prevent diseases associated with monocyte accumulation, lymphocyte accumulation or leukocyte accumulation are described herein.


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