The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 29, 2013

Filed:

Nov. 16, 2007
Applicants:

Efrat Ben-zeev, K. Motzkin, IL;

Vincent Jacques, Somerville, MA (US);

Yael Marantz, Kadma, IL;

A. Sekar Reddy, Burlington, MA (US);

Zhaoda Zhang, Andover, MA (US);

Oren Becker, Mevaseret Zion, IL;

Dilara Mccauley, Cambridge, MA (US);

Pini Orbach, Tel Mond, IL;

Sharon Shacham, Chestnut Hill, MA (US);

Ashis K. Saha, Stow, MA (US);

Michael Xie, Natick, MA (US);

Inventors:

Efrat Ben-Zeev, K. Motzkin, IL;

Vincent Jacques, Somerville, MA (US);

Yael Marantz, Kadma, IL;

A. Sekar Reddy, Burlington, MA (US);

Zhaoda Zhang, Andover, MA (US);

Oren Becker, Mevaseret Zion, IL;

Dilara McCauley, Cambridge, MA (US);

Pini Orbach, Tel Mond, IL;

Sharon Shacham, Chestnut Hill, MA (US);

Ashis K. Saha, Stow, MA (US);

Michael Xie, Natick, MA (US);

Assignee:

Microdose Therapeutx, Inc., Monmouth Junction, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); A01N 43/04 (2006.01); C07H 19/00 (2006.01); C07H 19/04 (2006.01); C07H 19/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are adenosine analog compounds of the general formula that act as P2Y receptors, e.g., the P2Yreceptor, including pharmaceutical compositions; and uses thereof to treat or prevent diseases associated with that receptor, e.g., disorders relating to mucus secretion, such as cystic fibrosis, chronic obstructive pulmonary disorder (COPD), asthma, constipation, chronic idiopathic constipation, dry mouth (xerostomia), gum disease, and gastrointestinal problems caused by radiation and chemotherapy for cancer.


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