The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2013
Filed:
Mar. 18, 2013
The Chemo-sero-therapeutic Research Institute, Kumamoto, JP;
Shintaro Kamei, Kumamoto, JP;
Asami Shindome, Kumamoto, JP;
Takayoshi Hamamoto, Kumamoto, JP;
Hiroaki Maeda, Kikuchi, JP;
Masaki Hirashima, Kikuchi, JP;
Sachio Okuda, Kumamoto, JP;
Misako Umehashi, Kumamoto, JP;
Sachie Ogawa, Cambridge, MA (US);
Megumi Imuta, Kawasaki, JP;
Norio Akaike, Kumamoto, JP;
Kazuo Takahama, Kumamoto, JP;
Ryoko Wada, Kumamoto, JP;
The Chemo-Sero-Therapeutic Research Institute, Kumamoto-shi, JP;
Ginkyo Academy Kumamoto Health Science University, Kumamoto-shi, JP;
National University Corporation Kumamoto University, Kumamoto-shi, JP;
Abstract
The activated Factor XI is provided as an antitussive for cough caused by the stimulation at the tracheal bifurcation such as chronic cough. A pharmaceutical composition for prevention, treatment and/or symptom amelioration of cough, comprising a polypeptide chain as an active ingredient and a pharmaceutically acceptable carrier, wherein the polypeptide chain consists of a full length amino acid sequence constituting activated Factor XI (hereinafter also referred to as 'FXIa'), the amino acid sequence with one or several amino acids therein being deleted, substituted or added, or a partial sequence of either of the above amino acid sequences, or an amino acid sequence comprising as a part any of the above amino acid sequences.