The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 29, 2013
Filed:
Nov. 05, 2005
Rosario Lizio, Rossdorf, DE;
Hans-ulrich Petereit, Darmstadt, DE;
Dave Trupti, Zwingenberg, DE;
Michael Gottschalk, Ober-Ramstadt, DE;
Rosario Lizio, Rossdorf, DE;
Hans-Ulrich Petereit, Darmstadt, DE;
Dave Trupti, Zwingenberg, DE;
Michael Gottschalk, Ober-Ramstadt, DE;
Evonik Röhm GmbH, Darmstadt, DE;
Abstract
The invention relates to an oral, multiparticulate form of administration, comprising pellets in the size ranging from 50 to 2500 $g(m)m which are substantially constituted of a) an inner matrix layer containing nanoparticles that contain a nucleic acid active ingredient and being embedded in a matrix of a polymer having a mucoadhesive effect, and b) an outer film coating, substantially consisting of an anionic polymer or copolymer that is optionally formulated with pharmaceutically conventional adjuvants, especially emollients.